profound state of unease or dissatisfaction. Dysphoria may accompany depression, anxiety, or agitation.It can also mean someone that is not comfortable in their current body, particularly in cases of gender dysphoria.

Cole, C.M., O’Boyle, M., Emory, L.E. et al. (1997). Comorbidity of Gender Dysphoria and Other Major Psychiatric Diagnoses. Archivesof Sex Behavior Vol. 26 Issue. 1 13-26.